Leveraging RNA as an informational molecule to revolutionize science and medicine
RNAs can fold into complex 3D structures with enormous potential to be targeted by small-molecule ligands
ForagR leverages highly selective chemical matter to bind unique and complex structures across the human transcriptome and identify druggable pockets in mRNAs that can be used to either increase or decrease protein expression
ForagR started with a blank slate, building a platform around the idea that RNA is a fundamentally different kind of drug target, one that demands its own innovations.
The ForagR platform harnesses RNA chemical genomics for transcriptome-wide target and ligand identification in cells, with early evaluation of the ability of small molecules to bind RNA and alter cellular protein levels. The ForagR approach unlocks the potential of targeting RNA to treat challenging diseases, including cancer and neurological disorders.
